The site of action of the fuzzy locus (fz) in the mouse, as determined by dermal-epidermal recombinations.
نویسندگان
چکیده
The site of action of the mutation fuzzy (fz) was investigated by the method of dermalepidermal recombination. Skins from 14-day mutant and normal mouse embryos were separated into dermal and epidermal components, recombined, and grown in the mouse testis for 14 days. Grafts that contained mutant epidermis as one of the components produced many abnormal hairs characteristic of fuzzy mice. There was no observable effect of the fz locus on the dermis under the conditions of this experiment.
منابع مشابه
The site of action of the naked locus (N) in the mouse as determined by dermal-epidermal recombinations.
The dermal-epidermal recombination technique was used to determine the site of action of the naked (N) locus in the skin of the mouse. The skin of athymic (nude) mice was used as a host site for growth of recombined epidermis and dermis from 13- and 14-day N/+ and +/+ embryos. Grafts that contained mutant epidermis lost their hair by 26 days after grafting (at the end of the first hair cycle) a...
متن کاملThe site of action of the ichthyosis locus (ic) in the mouse, as determined by dermal-epidermal recombinations.
Skin of 14-day icjic and + / + embryos was separated into dermal and epidermal layers using trypsin, and recombined in the combinations + /+ epidermis with + /+ dermis, +/ + epidermis with icfic dermis, icjic epidermis with + /+ dermis, and icjic epidermis with ic/ic dermis. The recombined tissues were implanted in adult histocompatible testes and allowed to grow for 2 weeks. The type of hair t...
متن کاملEvaluation of the relationship between clinicoepidemiological features of melasma and the level of involvement on wood’s lamp Examination
Background: Melasma is a common acquired hyperpigmentationdisorder often appearing on the face of young women. Melasmais classified into four groups based on Wood’s lamp examination:epidermal, dermal, mixed, and indeterminate. The goal of this studywas to evaluate the relationship between clinicoepidemiologicalcharacteristics of melasma and the level of involvement underWood’s lamp examination....
متن کاملComparison of genetic diversity and growth traits among Fangzheng silver crucian carp (Carassius auratus gibelio) gynogenetic clones
The silver crucian carp (Carassius auratus gibelio), a gynogenetic teleost, is a promising model for the study of evolutionary genetics in vertebrates. We identified ten gynogenetic clones (FZ-I~FZ-X) from triploid silver crucian carp, collected from Fangzheng County in Heilongjiang Province, China, using microsatellite markers. The genetic diversity of these gynogenetic clones was analyzed usi...
متن کاملComparison of genetic diversity and growth traits among Fangzheng silver crucian carp (Carassius auratus gibelio) gynogenetic clones
The silver crucian carp (Carassius auratus gibelio), a gynogenetic teleost, is a promising model for the study of evolutionary genetics in vertebrates. We identified ten gynogenetic clones (FZ-I~FZ-X) from triploid silver crucian carp, collected from Fangzheng County in Heilongjiang Province, China, using microsatellite markers. The genetic diversity of these gynogenetic clones was analyzed usi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of embryology and experimental morphology
دوره 32 3 شماره
صفحات -
تاریخ انتشار 1974